🧬 The Genes That Awaken Your Longevity: Scientific Keys to Living Longer and Better.

The genes that awaken your longevity: Scientific keys to loving longer and better

By Sonia Pérez Canales, CEO and Founder of Genetic Factor Longevity

Based on scientific evidence about FOXO3A, APOE, and SIRT1, and how nutrition, exercise, and rest can modulate their impact on longevity.

Why do some people age more slowly than others?

The answer isn’t just in habits—it lies in the interaction between our genes and our lifestyle. Today we know that certain genes are directly involved in longevity, meaning the body’s ability to remain functional, youthful, and resilient for longer.

These genes do not act alone. They are switched on or off depending on what we eat, our rest, physical activity, environment, and, of course, smart supplementation.

At Genetic Factor Longevity, we have worked for years to identify the most relevant genes for living longer and healthier. Below is a clear and understandable list of these genes, along with natural strategies to activate them.

10 Key Longevity Genes

1. FOXO3

·Function: Regulates oxidative stress, inflammation, and cellular repair.
·Why it matters: Known as the “longevity gene,” found in many centenarians.
·How to activate: Intermittent fasting, moderate exercise, low-sugar diet, green tea, resveratrol.

2. SIRT1 (And the SIRT Family)

· Function: Protects DNA, improves cellular repair, and regulates metabolism.
· How to activate: Caloric restriction, resveratrol, NAD+, physical exercise, fermented foods.

3. AMPK

·Function: Energy sensor that stimulates cellular autophagy (internal recycling of toxins and waste) and reduces systemic inflammation.
·How to activate: Gentle intermittent fasting, turmeric, berberine, resistance training, reducing refined sugars.
✅ Natural stimuli can activate the AMPK pathway without extreme restrictions, supporting cellular longevity and energy metabolism.

4. TP53

·Function: Known as “the guardian of the genome,” prevents cellular mutations.
·How to activate: Natural antioxidants, reducing toxins, quality sleep.

5. KLOTHO

·Function: Slows brain and vascular aging.
·How to activate: Omega-3 (soon available at Genetic Factor Longevity), aerobic exercise, vitamin D, moderate sun exposure.

6. Nrf2

·Function: Activates the production of endogenous antioxidants.
·How to activate: Broccoli, turmeric, green tea, sulforaphane, occasional 24-hour fasting (under professional guidance).

7. mTOR

·Function: Regulates cell growth and protein synthesis.
·How to regulate: Fasting, cycles of plant-based protein, digestive rest, regular physical activity.

8. PGC-1α

·Function: Stimulates mitochondrial biogenesis (more cellular energy).
·How to activate: High-intensity interval training (HIIT), cold exposure, coenzyme Q10.

9. LMNA

·Function: Related to nuclear structure and cellular aging.
·How to care for it: Manage chronic stress, restorative sleep, antioxidant support.

10. TERT

·Function: Involved in producing telomerase, the enzyme that protects telomeres.
·How to activate: Meditation, nutrient-rich diet, supplementation with astragalus or NAD+.

Can you awaken longevity starting today?

Yes. Genetics is not destiny—it’s a starting point. Everyone inherits certain genetic variants, but the epigenome (how genes are expressed) largely depends on lifestyle.

In other words: You cannot change your genes, but you can teach them to function better.

What role does supplementation play?

At Genetic Factor Longevity, we design formulas that directly support the activation of these key genes, using high-bioavailability ingredients, free from unnecessary additives, and backed by science.

Some of our products include:

• Spirulina: Rich in phycocyanin, modulates Nrf2, and reduces oxidative stress.

• Melatonin: Optimizes rest, supporting activation of repair genes like TP53.

• Tryptophan: Precursor to serotonin and melatonin, helps emotional balance.

• Vitamin D3: Essential for immune modulation and KLOTHO gene activation.

Conclusión

Awakening longevity is not magic—it’s science applied consciously.
Your genes are waiting for the right stimuli to function at their fullest. You choose whether to activate them or let them sleep.

At Genetic Factor Longevity, we invite you to start this journey with us. We don’t promise miracles; we promise knowledge, consistency, and a real commitment to your health.

This article is based on scientific studies on longevity genetics, with emphasis on variants like FOXO3A, APOE, and SIRT1, recognized for their roles in inflammation, oxidative stress, and metabolism. The interaction between these genes and lifestyle has been extensively supported by recent research.

Scientific Article Links:
·https://pmc.ncbi.nlm.nih.gov/articles/PMC7958462/?
·https://link.springer.com/article/10.1007/s00439-013-1342-z?
·https://pmc.ncbi.nlm.nih.gov/articles/PMC5403515/?